Aşırı Kilolu Kişilerde Olası Genotoksik Hasarın Analizi

AbstractObjective: Research has revealed that obesity changed the repair mechanism of DNA chain breaks. Also, increase in body mass index is found out to be associated with genomic instability. In this study, it was aimed investigate possible genotoxic damage overweight individuals.Material and Methods: present study level calculated Turkish adult peripheral blood samples using Single Cell Gel Electrophoresis assay. The results levels belonging people were compared statistically by SPSS analysis program normal-weight people.Results: Fifty five volunteers (21 normal weight 34 overweight); 23 women, mean age=30.13±7.97 32 men, age=38.13±10.63 participated study. Tail moment an average 1.21±0.45 all individuals. value as 1.29±0.46. When individuals (1.09±0.40), no significant difference determined (p>0.05). According results, between (p>0.05).Conclusion: first which gives information about relation being adults Turkey. presented there relationship according findings comet assay, we recommended new studies should conducted future different genotoxicity tests.